The start of the drive passes through rolling farm land and some good-sized towns and cities in northwestern Washington and southwestern British Columbia. Eventually it begins to follow the Fraser River, a very dry area that contrasts dramatically with the much wetter coastal region where Seattle and Vancouver sit. It then leaves the Fraser and Thompson Rivers behind and heads north towards Williams Lake across the Cariboo region, a dry plateau dominated by ranching and logging. North of Williams Lake the population thins even more, and Prince George, "BC's northern capital," seems a little larger than it should be by the time you reach it.
The drive from Prince George to Dawson Creek is mostly through boreal forest, except for one mountain pass and a few stretches, especially near the end, with some farming.